H7
Modify Date: 2024-01-04 16:13:41
H7 structure
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Common Name | H7 | ||
|---|---|---|---|---|
| CAS Number | 108930-17-2 | Molecular Weight | 364.291 | |
| Density | N/A | Boiling Point | 495.3ºC at 760mmHg | |
| Molecular Formula | C14H19Cl2N3O2S | Melting Point | 215-225 °C | |
| MSDS | Chinese USA | Flash Point | 253.3ºC | |
Use of H7PKC-IN-5 (compound H-7) is a potent PKC (protein kinase C) inhibitor. At 100 μM, PKC-IN-5 completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase)[1]. |
| Name | 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | PKC-IN-5 (compound H-7) is a potent PKC (protein kinase C) inhibitor. At 100 μM, PKC-IN-5 completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase)[1]. |
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| Related Catalog | |
| References |
| Boiling Point | 495.3ºC at 760mmHg |
|---|---|
| Melting Point | 215-225 °C |
| Molecular Formula | C14H19Cl2N3O2S |
| Molecular Weight | 364.291 |
| Flash Point | 253.3ºC |
| Exact Mass | 363.057495 |
| PSA | 70.68000 |
| LogP | 4.16870 |
| Vapour Pressure | 6E-10mmHg at 25°C |
| Storage condition | 2-8°C |
| Water Solubility | H2O: 20 mg/mL |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2935009090 |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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PKC enhances the capacity for secretion by rapidly recruiting covert voltage-gated Ca2+ channels to the membrane.
J. Neurosci. 35(6) , 2747-65, (2015) It is unknown whether neurons can dynamically control the capacity for secretion by promptly changing the number of plasma membrane voltage-gated Ca(2+) channels. To address this, we studied peptide r... |
| UNII:55VT8U9HB1 |
| Piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, dihydrochloride |
| 5-[(2-Methyl-1-piperazinyl)sulfonyl]isoquinoline dihydrochloride |
| 1-(5-Isoquinolinesulfonyl)-2-methyl-piperazine dihydrochloride |
| 5-[(2-Methylpiperazin-1-yl)sulfonyl]isoquinoline dihydrochloride |
| Isoquinoline, 5-[(2-methyl-1-piperazinyl)sulfonyl]-, hydrochloride (1:2) |
| 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine Dihydrochloride |
| MFCD00036961 |
| H-7 DIHYDROCHLORIDE |
| 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: H7
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: H7 dihydrochloride
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: H7 dihydrochloride
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: H-7 dihydrochloride
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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