H-7
H-7 structure
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Common Name | H-7 | ||
|---|---|---|---|---|
| CAS Number | 84477-87-2 | Molecular Weight | 291.36900 | |
| Density | 1.277 g/cm3 | Boiling Point | 495.3ºC at 760 mmHg | |
| Molecular Formula | C14H17N3O2S | Melting Point | 114 °C | |
| MSDS | Chinese USA | Flash Point | 253.3ºC | |
Use of H-7Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) and cyclic nucleotide dependent protein kinase, with a Ki of 6 μM for PKC[1]. |
| Name | 1-(5-isoquinolinesulfonyl)-2-methylpiperazine |
|---|---|
| Synonym | More Synonyms |
| Description | Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) and cyclic nucleotide dependent protein kinase, with a Ki of 6 μM for PKC[1]. |
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| Related Catalog | |
| Target |
PKC:6 μM (Ki) |
| References |
| Density | 1.277 g/cm3 |
|---|---|
| Boiling Point | 495.3ºC at 760 mmHg |
| Melting Point | 114 °C |
| Molecular Formula | C14H17N3O2S |
| Molecular Weight | 291.36900 |
| Flash Point | 253.3ºC |
| Exact Mass | 291.10400 |
| PSA | 70.68000 |
| LogP | 2.56470 |
| Index of Refraction | 1.652 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | TL9305000 |
| HS Code | 2935009090 |
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H-7 CAS#:84477-87-2 |
| Literature: Morikawa; Sone; Asano Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 3 p. 770 - 773 |
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H-7 CAS#:84477-87-2 |
| Literature: Morikawa; Sone; Asano Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 3 p. 770 - 773 |
|
~%
H-7 CAS#:84477-87-2 |
| Literature: Morikawa; Sone; Asano Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 3 p. 770 - 773 |
| Precursor 3 | |
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| DownStream 0 | |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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| H-7 dihydrochloride,(±)-1-(5-Isoquinolinesulphonyl)-2-methylpiperazinedihydrochloride |
| H-7 |
| H-72HCl |