CTP 518(Atazanavir, deuterated)
Modify Date: 2024-01-17 20:38:12
CTP 518(Atazanavir, deuterated) structure
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Common Name | CTP 518(Atazanavir, deuterated) | ||
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| CAS Number | 1092540-56-1 | Molecular Weight | 719.95 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C38H37D15N6O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CTP 518(Atazanavir, deuterated)Atazanavir-d15 is the d15 labled Atazanavir (HY-17367). Atazanavir is a selective HIV-1 protease inhibitor[1]. |
| Name | trideuteriomethyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-4-phenyl-3-[[(2S)-4,4,4-trideuterio-2-(trideuteriomethoxycarbonylamino)-3,3-bis(trideuteriomethyl)butanoyl]amino]butyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate |
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| Synonym | More Synonyms |
| Description | Atazanavir-d15 is the d15 labled Atazanavir (HY-17367). Atazanavir is a selective HIV-1 protease inhibitor[1]. |
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| Related Catalog | |
| Target |
HIV-1 |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C38H37D15N6O7 |
| Molecular Weight | 719.95 |
| Exact Mass | 719.483887 |
| PSA | 185.18000 |
| LogP | 5.20 |
| Index of Refraction | 1.562 |
| (H)Methyl [(5S,10S,11S,14S)-11-benzyl-10-hydroxy-15,15-bis[(H)methyl]-5-(2-methyl-2-propanyl)-3,6,13-trioxo-8-[4-(2-pyridinyl)benzyl](1,1,1,16,16,16-H)-2-oxa-4,7,8,12-tetraazahexadec 
an-14-yl]carbamate |
| Butanoic acid, 3,3-dimethyl-2-[[(methyl-d-oxy)carbonyl]amino]-, 2-[(2S,3S)-3-[[(2S)-3,3-di(methyl-d)-2-[[(methyl-d-oxy)carbonyl]amino]-1-oxobutyl-4,4,4-d]amino]-2-hydroxy-4-phenylbutyl]-2-
 [[4-(2-pyridinyl)phenyl]methyl]hydrazide, (2S)- |
| y0306 |