2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine

Modify Date: 2024-02-01 14:56:45

2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine Structure
2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine structure
Common Name 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine
CAS Number 1093278-52-4 Molecular Weight 299.26
Density 1.9±0.1 g/cm3 Boiling Point 660.7±65.0 °C at 760 mmHg
Molecular Formula C11H14FN5O4 Melting Point N/A
MSDS N/A Flash Point 353.4±34.3 °C

 Use of 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine


2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2-methoxy-9H-purin-6-amine
Synonym More Synonyms

  Biological Activity

Description 2-Methoxy-2’-deoxy-2’-fluoro-beta-D-arabinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 660.7±65.0 °C at 760 mmHg
Molecular Formula C11H14FN5O4
Molecular Weight 299.26
Flash Point 353.4±34.3 °C
Exact Mass 299.102997
LogP -1.55
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.773

 Synonyms

9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2-methoxy-9H-purin-6-amine
9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2-methoxy-
MFCD25542487