![]() gamma-secretase modulator 2 structure
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Common Name | gamma-secretase modulator 2 | ||
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CAS Number | 1093978-89-2 | Molecular Weight | 514.47500 | |
Density | 1.43 g/cm3 | Boiling Point | 729.8ºC at 760 mmHg | |
Molecular Formula | C25H22F4N6O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 395.2ºC |
Use of gamma-secretase modulator 2gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's diseaseIC50 value: Target: γ-secretaseγ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease. |
Name | 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one |
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Synonym | More Synonyms |
Description | gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's diseaseIC50 value: Target: γ-secretaseγ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease. |
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Related Catalog |
Density | 1.43 g/cm3 |
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Boiling Point | 729.8ºC at 760 mmHg |
Molecular Formula | C25H22F4N6O2 |
Molecular Weight | 514.47500 |
Flash Point | 395.2ºC |
Exact Mass | 514.17400 |
PSA | 78.07000 |
LogP | 4.73470 |
Storage condition | 2-8℃ |
~% gamma-secretase... CAS#:1093978-89-2 |
Literature: WO2008/156580 A1, ; Page/Page column 43-44 ; WO 2008/156580 A1 |
Precursor 2 | |
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DownStream 0 |
2H-1-Benzopyran-2-carbonitrile,6-fluoro-3,4-dihydro-4-oxo |
6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one |
6-fluoro-3,4-dihydro-4-oxo-2H-1-benzopyran-2-carbonitrile |
gamma-secretase modulator 2 |