Neocryptotanshinone

Modify Date: 2024-01-09 17:26:41

Neocryptotanshinone structure	Common Name	Neocryptotanshinone
	CAS Number	109664-02-0	Molecular Weight	314.37600
	Density	1.255g/cm3	Boiling Point	505.3ºC at 760 mmHg
	Molecular Formula	C₁₉H₂₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	273.5ºC

Use of Neocryptotanshinone

Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways[1][2].

Name	1-hydroxy-2-(1-hydroxypropan-2-yl)-8,8-dimethyl-6,7-dihydro-5H-phenanthrene-3,4-dione
Synonym	More Synonyms

Description	Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology
References	[1]. Chuanhong Wu, et al. Neocryptotanshinone Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages by Suppression of NF-κB and iNOS Signaling Pathways. Acta Pharm Sin B. 2015 Jul;5(4):323-9. [2]. H C Lin, et al. Two New Fatty Diterpenoids From Salvia Miltiorrhiza. J Nat Prod. 2001 May;64(5):648-50.

Description

Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways[1][2].

Related Catalog

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

References

[1]. Chuanhong Wu, et al. Neocryptotanshinone Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages by Suppression of NF-κB and iNOS Signaling Pathways. Acta Pharm Sin B. 2015 Jul;5(4):323-9.

[2]. H C Lin, et al. Two New Fatty Diterpenoids From Salvia Miltiorrhiza. J Nat Prod. 2001 May;64(5):648-50.

Density	1.255g/cm3
Boiling Point	505.3ºC at 760 mmHg
Molecular Formula	C₁₉H₂₂O₄
Molecular Weight	314.37600
Flash Point	273.5ºC
Exact Mass	314.15200
PSA	74.60000
LogP	2.96340
Vapour Pressure	4.93E-11mmHg at 25°C
Index of Refraction	1.602
Water Solubility	Insuluble (2.8E-3 g/L) (25 ºC)

Hazard Codes	Xi

Precursor 9
CAS#:171979-72-9 3-((S)-1-((tert... CAS#:879000-44-9 11,14-dioxo-12,... CAS#:2270-59-9 5-Bromo-2-methy... CAS#:578-57-4 bromoanisole
CAS#:171979-69-4 1,1-dimethyl-5-... CAS#:33214-70-9 5-methoxy-1,1-d... CAS#:100-66-3 Anisole CAS#:171979-70-7 1-(1'-methoxyph...
CAS#:35825-57-1 Cryptotanshinone
DownStream 2
CAS#:35825-57-1 Cryptotanshinone CAS#:568-72-9 Tanshinone IIA