D,L-erythro-PDMP
Modify Date: 2024-01-16 14:05:23
D,L-erythro-PDMP structure
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Common Name | D,L-erythro-PDMP | ||
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| CAS Number | 109760-77-2 | Molecular Weight | 390.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H38N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of D,L-erythro-PDMPD,L-erythro-PDMP is a erythro isomer of glucosylceramide synthase inhibitor[1][2]. |
| Name | d,l-erythro-1-phenyl-2-decanoylamino-3-morpholino-1-propanol hcl |
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| Synonym | More Synonyms |
| Description | D,L-erythro-PDMP is a erythro isomer of glucosylceramide synthase inhibitor[1][2]. |
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| Related Catalog | |
| In Vitro | D,L-erythro-PDMP (0, 12, 25, 50 μM; 0, 4, 7, 10 days) shows a inhibitory effect on cell growth of rabbit skin fibroblasts[1]. D,L-erythro PDMP (50 μM; 3 days) has eytotoxic of rabbit skin fibroblasts on cell morphology[1]. D,L-erythro-PDMP do not affect the biosynthesis of glycosphingolipids[1]. D,L-erythro-PDMP (MDCK cells; 40 μM; 24 h) induces a marked increase in glucosyltransferase specific activity: 14.6 nmol/h per mg protein[2]. D,L-erythro-PDMP (40 μM; 6 h) protects the cells against loss of synthase in cells exposes to cycloheximide[2]. Cell Proliferation Assay[1] Cell Line: rabbit skin fibroblast Concentration: 0, 12, 25, 50 μM Incubation Time: 0, 4, 7, 10 days Result: Showed a inhibitory effect on cell growth. Cell Cytotoxicity Assay[1] Cell Line: rabbit skin fibroblast Concentration: 50 μM Incubation Time: 3 days Result: Had eytotoxic on cell morphology. |
| References |
| Molecular Formula | C23H38N2O3 |
|---|---|
| Molecular Weight | 390.56 |
| Exact Mass | 426.26500 |
| PSA | 61.80000 |
| LogP | 4.80850 |
| Hazard Codes | Xi |
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| d,l-erythro-pdmp |