D,L-erythro-PDMP

Modify Date: 2024-01-16 14:05:23

D,L-erythro-PDMP structure	Common Name	D,L-erythro-PDMP
	CAS Number	109760-77-2	Molecular Weight	390.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₃₈N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of D,L-erythro-PDMP

D,L-erythro-PDMP is a erythro isomer of glucosylceramide synthase inhibitor[1][2].

Name	d,l-erythro-1-phenyl-2-decanoylamino-3-morpholino-1-propanol hcl
Synonym	More Synonyms

Description	D,L-erythro-PDMP is a erythro isomer of glucosylceramide synthase inhibitor[1][2].
Related Catalog	Research Areas >> Others
In Vitro	D,L-erythro-PDMP (0, 12, 25, 50 μM; 0, 4, 7, 10 days) shows a inhibitory effect on cell growth of rabbit skin fibroblasts[1]. D,L-erythro PDMP (50 μM; 3 days) has eytotoxic of rabbit skin fibroblasts on cell morphology[1]. D,L-erythro-PDMP do not affect the biosynthesis of glycosphingolipids[1]. D,L-erythro-PDMP (MDCK cells; 40 μM; 24 h) induces a marked increase in glucosyltransferase specific activity: 14.6 nmol/h per mg protein[2]. D,L-erythro-PDMP (40 μM; 6 h) protects the cells against loss of synthase in cells exposes to cycloheximide[2]. Cell Proliferation Assay[1] Cell Line: rabbit skin fibroblast Concentration: 0, 12, 25, 50 μM Incubation Time: 0, 4, 7, 10 days Result: Showed a inhibitory effect on cell growth. Cell Cytotoxicity Assay[1] Cell Line: rabbit skin fibroblast Concentration: 50 μM Incubation Time: 3 days Result: Had eytotoxic on cell morphology.
References	[1]. [1] Uemura K, et al. Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts. J Biochem. 1990 Oct;108(4):525-30. [2]. [2] Abe A, et al. Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta. 1996 Feb 16;1299(3):333-41.

Molecular Formula	C₂₃H₃₈N₂O₃
Molecular Weight	390.56
Exact Mass	426.26500
PSA	61.80000
LogP	4.80850

Hazard Codes	Xi

d,l-erythro-pdmp

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: D,L-erythro-PDMP
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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