D-Glucose-13C6

Modify Date: 2024-01-05 10:23:04

D-Glucose-13C6 Structure
D-Glucose-13C6 structure
Common Name D-Glucose-13C6
CAS Number 110187-42-3 Molecular Weight 186.11200
Density 1.581g/cm3 Boiling Point N/A
Molecular Formula 13C6H12O6 Melting Point 150-152ºC(lit.)
MSDS USA Flash Point N/A

 Use of D-Glucose-13C6


D-Glucose-13C6 is a tracer used to trace glucose-related synthetic catabolism, is a low-cost alternative with the significant advantage that the sixth isotope of natural glucose has virtually zero natural abundance, which facilitates isotopomer analysis with <1% labeled glucose in the infusate[1][2].

 Names

Name Glucose-13C
Synonym More Synonyms

 D-Glucose-13C6 Biological Activity

Description D-Glucose-13C6 is a tracer used to trace glucose-related synthetic catabolism, is a low-cost alternative with the significant advantage that the sixth isotope of natural glucose has virtually zero natural abundance, which facilitates isotopomer analysis with <1% labeled glucose in the infusate[1][2].
References

[1]. Malz F, et al. Synthesis of methyl 4'-O-methyl-beta-D-cellobioside-13C12 from D-glucose-13C6. Part 2: solid-state NMR studies. Carbohydr Res. 2007 Jan 15;342(1):65-70.

[2]. Zhang H, et al. A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer. Clin Chem. 2009 Mar;55(3):527-32.

 Chemical & Physical Properties

Density 1.581g/cm3
Melting Point 150-152ºC(lit.)
Molecular Formula 13C6H12O6
Molecular Weight 186.11200
Exact Mass 186.08400
PSA 110.38000
Index of Refraction 1.573

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Articles7

More Articles
A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer.

Clin. Chem. 55 , 527-532, (2009)

The isotope-labeled intravenous glucose tolerance test (IVGTT) combined with computer modeling is widely used to derive parameters related to glucose metabolism in vivo. Most of these methods involve ...

Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress.

BMC Biochem. 6 , 4, (2005)

Heat shock factor (HSF/HSF1) not only is the transcription factor primarily responsible for the transcriptional response of cells to physical and chemical stress but also coregulates other important s...

A convenient gram-scale synthesis of uridine diphospho(13C6)glucose.

Carbohydr. Res. 341 , 1743-1747, (2006)

A simple gram-scale synthesis of uridine diphospho(13C6)glucose is presented from D-(13C6)glucose. The critical step uses a 1H-tetrazole-catalyzed coupling of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyran...

 Synonyms

D-Glucose-ul-13C,Dextrose-13C6
2,3,4,5,6-pentahydroxyhexanal
MFCD00037544
D-Glucose-ul-13C,Dextrose-13C6,Labeled Glucose
D-Glucose (U-13C6, 24-25%)