N6-(4-Hydroxybenzyl)adenosine

Modify Date: 2024-01-10 07:20:35

N6-(4-Hydroxybenzyl)adenosine Structure
N6-(4-Hydroxybenzyl)adenosine structure
Common Name N6-(4-Hydroxybenzyl)adenosine
CAS Number 110505-75-4 Molecular Weight 373.36300
Density N/A Boiling Point N/A
Molecular Formula C17H19N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N6-(4-Hydroxybenzyl)adenosine


N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM). IC50 value: 6.77-141 μMTarget: P2Y12receptorAnti-aggregation activity of N6-(4-Hydroxybenzyl)adenosine could involve an interaction with the P2Y12receptor binding site.

 Names

Name (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[(4-hydroxyphenyl)methylamino]purin-9-yl]oxolane-3,4-diol
Synonym More Synonyms

 N6-(4-Hydroxybenzyl)adenosine Biological Activity

Description N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM). IC50 value: 6.77-141 μMTarget: P2Y12receptorAnti-aggregation activity of N6-(4-Hydroxybenzyl)adenosine could involve an interaction with the P2Y12receptor binding site.
Related Catalog
References

[1]. Vistoli G, et al. Naturally occurring N(6)-substituted adenosines (cytokinin ribosides) are in vitro inhibitors of platelet aggregation: an in silico evaluation of their interaction with the P2Y(12) receptor. Bioorg Med Chem Lett. 2014 Dec 15;24(24):5652-

[2]. Zhang, Ying; Shi, Jian-gong; Liu, Geng-tao; Zhang, Jian-jun. Effect of N6-(4-hydroxybenzyl) adenine riboside isolated from Gastrodia elata on muscle strength, motor coordination and body temperature in mice. From Guoji Yaoxue Yanjiu Zazhi (2012), 39(5), 4

 Chemical & Physical Properties

Molecular Formula C17H19N5O5
Molecular Weight 373.36300
Exact Mass 373.13900
PSA 145.78000

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

N6-(4-Hydroxybenzyl)-adenosine
Adenosine,N-[(4-hydroxyphenyl)methyl]
N6-(4-hydroxybenzyl)adenine riboside
N6-(4-Hydroxybenzyl)adenosine