A2AR-agonist-1

Modify Date: 2024-01-10 08:30:33

A2AR-agonist-1 structure	Common Name	A2AR-agonist-1
	CAS Number	41552-95-8	Molecular Weight	410.42600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₂N₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of A2AR-agonist-1

A2AR-agonist-1 is a potent A2AR and ENT1 agonist with Ki of 4.39 and 3.47 for A2AR and ENT1.IC50 value: 4.39 and 3.47 (Ki) [1]Target: A2AR and ENT1A2AR-agonist-1 is a novel dual-action compound, targeting the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection.[1]

Name	N6-[(1H-indole-3-yl)ethyl]adenosine
Synonym	More Synonyms

Description	A2AR-agonist-1 is a potent A2AR and ENT1 agonist with Ki of 4.39 and 3.47 for A2AR and ENT1.IC50 value: 4.39 and 3.47 (Ki) [1]Target: A2AR and ENT1A2AR-agonist-1 is a novel dual-action compound, targeting the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection.[1]
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor Research Areas >> Neurological Disease
References	[1]. Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-1400. [2]. Lin Yun-Lian, et al. Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases. From PCT Int. Appl. (2012), WO 2012064340 A1 20120518. [3]. Chen, Chih-Cheng, et al. Methods and compositions for treating pain. From PCT Int. Appl. (2013), WO 2013120078 A1 20130815.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

Research Areas >> Neurological Disease

References

[1]. Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-1400.

[2]. Lin Yun-Lian, et al. Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases. From PCT Int. Appl. (2012), WO 2012064340 A1 20120518.

[3]. Chen, Chih-Cheng, et al. Methods and compositions for treating pain. From PCT Int. Appl. (2013), WO 2013120078 A1 20130815.

Molecular Formula	C₂₀H₂₂N₆O₄
Molecular Weight	410.42600
Exact Mass	410.17000
PSA	141.34000
LogP	0.64670
Storage condition	2-8℃

N6-(4-hydroxybenzyl)adenosine

N6-(2-(3-indolyl)ethyl)adenosine

N6-[2-(indol-3-yl)ethyl]adenosine

(2R,3S,4R,5R)-2-Hydroxymethyl-5-{6-[2-(1H-indol-3-yl)-ethylamino]-purin-9-yl}-tetrahydro-furan-3,4-diol

6-[2-(3-Indolyl)ethylamino]-9-(β-D-ribofuranosyl)purine

N6-(2-indol-3-yl-ethyl)-adenosine

A2AR-agonist-1

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China
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DC Chemicals Limited
China
Product Name: A2AR agonist-1
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Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Price: $462/10mM*1mLinDMSO

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A2AR-agonist-1

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