TREM2 agonist-1

Modify Date: 2024-06-08 17:58:12

TREM2 agonist-1 Structure
TREM2 agonist-1 structure
Common Name TREM2 agonist-1
CAS Number 2738486-70-7 Molecular Weight 437.90
Density N/A Boiling Point N/A
Molecular Formula C23H21ClFN5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TREM2 agonist-1


TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50 between 3.0 μM and 100 μM)[1].

 Names

Name TREM2 agonist-1

 TREM2 agonist-1 Biological Activity

Description TREM2 agonist-1 (I-246) is a triggering receptor expressed on myeloid cells 2 (TREM2) agonist (EC50 between 3.0 μM and 100 μM)[1].
Related Catalog
In Vitro TREM2 agonist-1 (0-100 μM; 16 h) treatment activates hTREM2 in HEK293 cell[1]. Cell Viability Assay[1] Cell Line: HEK293 cells Concentration: 0-100 μM Incubation Time: 16 hours Result: Showed an EC50 value between 3.0 μM and 100 μM.
References

[1]. Lara C. CZABANIUK, et al. Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use. WO2021226629A1.

 Chemical & Physical Properties

Molecular Formula C23H21ClFN5O
Molecular Weight 437.90