CB2R agonist 1

Modify Date: 2024-03-03 19:16:53

CB2R agonist 1 structure	Common Name	CB2R agonist 1
	CAS Number	1817633-49-0	Molecular Weight	340.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₂N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CB2R agonist 1

CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role[1].

Name	CB2R agonist 1

Description	CB2R agonist 1 is a selective ligand of cannabinoid receptor subtype 2 (CB2R) with an EC50 value of 0.56 µM. CB2R agonist 1 has high affinity and excellent selectivity for human CB2R and CB1R respectively. CB2R agonist 1 regulates the production of pro-inflammatory cytokines and anti-inflammatory cytokines and play an immunomodulatory role[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
Target	CB2R:0.56 μM (EC50)
In Vitro	CB2R agonist 1 (Compound 4) (1 和 10 μM；24 h) 以浓度依赖性方式增加单核细胞和巨噬细胞中 IL-4、IL-10 抗炎细胞因子的产生，减少 TNF-α、IFN-γ、IL-1β、IL-6 的产生[1]。
References	[1]. Graziano G, et al. N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R). Eur J Med Chem. 2023 Feb 15;248:115109.

Molecular Formula	C₂₂H₃₂N₂O
Molecular Weight	340.50

CB2R agonist 1

Use of CB2R agonist 1

Names

CB2R agonist 1 Biological Activity

Chemical & Physical Properties