Ethyl Oleate

Modify Date: 2024-01-02 18:15:51

Ethyl Oleate Structure
Ethyl Oleate structure
 Common Name Ethyl Oleate
CAS Number 111-62-6 Molecular Weight 310.514
Density 0.87 g/mL at 25 °C(lit.) Boiling Point 216-218 °C15 mm Hg
Molecular Formula C20H38O2 Melting Point −32 °C(lit.)
MSDS Chinese USA Flash Point 91.8±20.4 °C

 Use of Ethyl Oleate


Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs). NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration[1].

 Names

Name ethyl oleate
Synonym More Synonyms

 Ethyl Oleate Biological Activity

Description Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. Ethyl oleate is the liquid lipid component in nanostructured lipid carriers (NLCs). NLC is a promising vehicle for oral trans-Ferulic acid (TFA) administration[1].
Related Catalog
References

[1]. Zhang Y, et al. Ethyl oleate-containing nanostructured lipid carriers improve oral bioavailability of trans-ferulic acid ascompared with conventional solid lipid nanoparticles. Int J Pharm. 2016 Sep 10;511(1):57-64.

 Chemical & Physical Properties

Density 0.87 g/mL at 25 °C(lit.)
Boiling Point 216-218 °C15 mm Hg
Melting Point −32 °C(lit.)
Molecular Formula C20H38O2
Molecular Weight 310.514
Flash Point 91.8±20.4 °C
Exact Mass 310.287170
PSA 26.30000
LogP 8.69
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.455
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RG3715000
CHEMICAL NAME :
9-Octadecenoic acid (Z)-, ethyl ester
CAS REGISTRY NUMBER :
111-62-6
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C20-H38-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,683,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,683,1982

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes F
Safety Phrases S23-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS RG3715000
HS Code 2916150000

 Synthetic Route

 Customs

HS Code 2916150000
Summary 2916150000 oleic, linoleic or linolenic acids, their salts and esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles42

More Articles
Fatty acid ethyl esters disrupt neonatal alveolar macrophage mitochondria and derange cellular functioning.

Alcohol. Clin. Exp. Res. 39(3) , 434-44, (2015)

Chronic alcohol exposure alters the function of alveolar macrophages (AM), impairing immune defenses in both adult and neonatal lungs. Fatty acid ethyl esters (FAEEs) are biological markers of prenata...

N-trimethyl chitosan (TMC)-modified microemulsions for improved oral bioavailability of puerarin: preparation and evaluation.

Drug Deliv. 22 , 516-21, (2015)

The aim of this research was to increase the oral bioavailability of puerarin by N-trimethyl chitosan-modified microemulsions (TMC-MEs) loaded with puerarin. Different concentrations of TMC-modified m...

Transcutaneous delivery of leflunomide nanoemulgel: Mechanistic investigation into physicomechanical characteristics, in vitro anti-psoriatic and anti-melanoma activity.

Int. J. Pharm. 487 , 148-56, (2015)

The present study is a mechanistic validation of 'proof of concept' of effective topical delivery of leflunomide (LFD) nanoemulgel for localized efficient treatment of psoriatic lesions as well as mel...

 Synonyms

ethylis oleas
MFCD00009579
ETHYLOLEATE,NF
EINECS 203-889-5
Ethylis oleas,Oleic acid ethyl ester
Oleic acid ethyl
oleic acid ethyl ester
Ethyloleat
oleic
Ethyl oleate
Esterol 123
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Chemsrc provides Ethyl Oleate(CAS#:111-62-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Ethyl Oleate are included as well.>> amp version: Ethyl Oleate

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