Capecitabine-d11
Modify Date: 2024-01-06 14:35:02
Capecitabine-d11 structure
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Common Name | Capecitabine-d11 | ||
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| CAS Number | 1132662-08-8 | Molecular Weight | 370.418 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C15H11D11FN3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Capecitabine-d11Capecitabine-d11 is the deuterium labeled Capecitabine. Capecitabine is an oral prodrug that is converted to its active metabolite, 5-FU, by thymidine phosphorylase[1][2]. |
| Name | Capecitabine-d11 |
|---|---|
| Synonym | More Synonyms |
| Description | Capecitabine-d11 is the deuterium labeled Capecitabine. Capecitabine is an oral prodrug that is converted to its active metabolite, 5-FU, by thymidine phosphorylase[1][2]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
[2]. PharmD CM, et al. Capecitabine: A review. Clinical Therapeutics. 2005 Jan; 27(1): 23-44. |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C15H11D11FN3O6 |
| Molecular Weight | 370.418 |
| Exact Mass | 370.218323 |
| PSA | 126.40000 |
| LogP | 0.97 |
| Index of Refraction | 1.600 |
| 5'-Deoxy-5-fluoro-N-{[(H)pentyloxy]carbonyl}cytidine |
| Cytidine, 5'-deoxy-5-fluoro-N-[(pentyl-d-oxy)carbonyl]- |
| 1,1,2,2,3,3,4,4,5,5,5-undecadeuteriopentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate |