H-Gly-Arg-Gly-Asp-Asn-Pro-OH

Modify Date: 2024-01-02 08:25:26

H-Gly-Arg-Gly-Asp-Asn-Pro-OH Structure
H-Gly-Arg-Gly-Asp-Asn-Pro-OH structure
 Common Name H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS Number 114681-65-1 Molecular Weight 614.61
Density 1.7±0.1 g/cm3 Boiling Point N/A
Molecular Formula C23H38N10O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H-Gly-Arg-Gly-Asp-Asn-Pro-OH


RGD peptide acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].

 Names

Name H-Gly-Arg-Gly-Asp-Asn-Pro-OH
Synonym More Synonyms

 H-Gly-Arg-Gly-Asp-Asn-Pro-OH Biological Activity

Description RGD peptide acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].
Related Catalog
References

[1]. Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996).

[2]. Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50.

[3]. Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Molecular Formula C23H38N10O10
Molecular Weight 614.61
Exact Mass 614.277222
PSA 342.32000
LogP -3.41
Index of Refraction 1.696
Storage condition -15°C

 Synonyms

REF DUPL: Gly-Arg-Gly-Asp-Asn-Pro
Glycyl-N-(diaminomethylene)-L-ornithylglycyl-L-α-aspartyl-L-asparaginyl-L-proline
RGD PEPTIDE
GRGDNP
L-Proline, glycyl-N-(diaminomethylene)-L-ornithylglycyl-L-α-aspartyl-L-asparaginyl-
Gly-Arg-Gly-Asp-Asn-Ser
GLY-ARG-GLY-ASP-ASN-PRO
RGD PEPTIDE (GRGDNP)
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