114681-65-1

114681-65-1 structure

Name: H-Gly-Arg-Gly-Asp-Asn-Pro-OH
Chemical Name: H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS Number: 114681-65-1
Molecular Formula: C₂₃H₃₈N₁₀O₁₀
Molecular Weight: 614.61
Catalog: Biochemical Amino acids and their derivatives Asparagine derivatives
Create Date: 2018-08-01 13:10:00
Modify Date: 2024-01-02 08:25:26
RGD peptide acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].

Name	H-Gly-Arg-Gly-Asp-Asn-Pro-OH
Synonyms	REF DUPL: Gly-Arg-Gly-Asp-Asn-Pro Glycyl-N-(diaminomethylene)-L-ornithylglycyl-L-α-aspartyl-L-asparaginyl-L-proline RGD PEPTIDE GRGDNP L-Proline, glycyl-N-(diaminomethylene)-L-ornithylglycyl-L-α-aspartyl-L-asparaginyl- Gly-Arg-Gly-Asp-Asn-Ser GLY-ARG-GLY-ASP-ASN-PRO RGD PEPTIDE (GRGDNP)

Description	RGD peptide acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Cytoskeleton >> Integrin
References	[1]. Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996). [2]. Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50. [3]. Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.