(+)-PHENSERINE

Modify Date: 2024-01-10 15:57:06

(+)-PHENSERINE Structure
(+)-PHENSERINE structure
Common Name (+)-PHENSERINE
CAS Number 116839-68-0 Molecular Weight 337.41600
Density N/A Boiling Point N/A
Molecular Formula C20H23N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (+)-PHENSERINE


(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.

 Names

Name (3aR,8aS)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]i ndol-5-yl phenylcarbamate
Synonym More Synonyms

 (+)-PHENSERINE Biological Activity

Description (+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.
Related Catalog
Target

IC50: 45.3 μM (AChE), Ki: 48 μM (AChE).

References

[1]. al-Jafari AA, et al. Kinetics of human erythrocyte acetylcholinesterase inhibition by a novel derivative of physostigmine: phenserine. Biochem Biophys Res Commun. 1998 Jul 9; 248(1):180-5.

 Chemical & Physical Properties

Molecular Formula C20H23N3O2
Molecular Weight 337.41600
Exact Mass 337.17900
PSA 48.30000
LogP 3.68310

 Synonyms

(+)-PHENSERINE
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