116839-68-0

116839-68-0 structure

Name: (+)-PHENSERINE
Chemical Name: (3aR,8aS)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]i ndol-5-yl phenylcarbamate
CAS Number: 116839-68-0
Molecular Formula: C₂₀H₂₃N₃O₂
Molecular Weight: 337.41600
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2017-08-23 09:26:31
Modify Date: 2024-01-10 15:57:06
(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.

Name	(3aR,8aS)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]i ndol-5-yl phenylcarbamate
Synonyms	(+)-PHENSERINE

Description	(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> AChE Research Areas >> Neurological Disease Research Areas >> Endocrinology
Target	IC50: 45.3 μM (AChE), Ki: 48 μM (AChE).
References	[1]. al-Jafari AA, et al. Kinetics of human erythrocyte acetylcholinesterase inhibition by a novel derivative of physostigmine: phenserine. Biochem Biophys Res Commun. 1998 Jul 9; 248(1):180-5.