CDK4/6-IN-16
Modify Date: 2024-02-05 23:05:58
CDK4/6-IN-16 structure
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Common Name | CDK4/6-IN-16 | ||
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| CAS Number | 1169694-98-7 | Molecular Weight | 504.602 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 729.5±70.0 °C at 760 mmHg | |
| Molecular Formula | C27H33FN8O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 395.0±35.7 °C | |
Use of CDK4/6-IN-16CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer[1]. |
| Name | 2-{[(1-{6-[(9-Cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl}-4-piperidinyl)methyl]amino}ethanol |
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| Synonym | More Synonyms |
| Description | CDK4/6-IN-16 (example 195) is a potent CDK4 and CDK6 inhibitor, with an IC50 of 0.013 μM for CDK4. CDK4/6-IN-16 can be used for the research of CDK4-mediated disorders, such as cancer[1]. |
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| Related Catalog | |
| Target |
CDK4:13 nM (IC50) CDK6 |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 729.5±70.0 °C at 760 mmHg |
| Molecular Formula | C27H33FN8O |
| Molecular Weight | 504.602 |
| Flash Point | 395.0±35.7 °C |
| Exact Mass | 504.276123 |
| LogP | 1.86 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.735 |
| Ethanol, 2-[[[1-[6-[(9-cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-4-piperidinyl]methyl]amino]- |
| 2-{[(1-{6-[(9-Cyclopentyl-8-fluoro-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl}-4-piperidinyl)methyl]amino}ethanol |