SOR-C13

Modify Date: 2024-04-07 18:13:16

SOR-C13 structure	Common Name	SOR-C13
	CAS Number	1187852-48-7	Molecular Weight	1565.81
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₂H₁₁₆N₂₀O₁₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SOR-C13

SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity[1].

Name	SOR-C13

Description	SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel that is associated with malignancy and poor prognosis in breast cancer. SOR-C13 has anticancer activity[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cancer
In Vivo	SOR-C13 (i.p.; 400,600 or 800 mg/kg; daily; on days 1 to 12) can effectively inhibit the growth of tumor in female NOD/SCID mice with SKOV-3 cell[2].
References	[1]. S Fu , et al. Erratum to: First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors. Invest New Drugs. 2017 Jun;35(3):397. [2]. Hui Xue, et al. Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model. J Cancer. 2018 Aug 6;9(17):3196-3207.

Molecular Formula	C₇₂H₁₁₆N₂₀O₁₉
Molecular Weight	1565.81

Taiwan Oyi peptide Co. Ltd
China
Product Name: SOR-C13
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

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