Fmoc-NH-(PEG)9-CH2CH2COOH

Modify Date: 2024-01-08 15:36:43

Fmoc-NH-(PEG)9-CH2CH2COOH Structure
Fmoc-NH-(PEG)9-CH2CH2COOH structure
Common Name Fmoc-NH-(PEG)9-CH2CH2COOH
CAS Number 1191064-81-9 Molecular Weight 707.805
Density 1.2±0.1 g/cm3 Boiling Point 803.9±65.0 °C at 760 mmHg
Molecular Formula C36H53NO13 Melting Point N/A
MSDS N/A Flash Point 440.0±34.3 °C

 Use of Fmoc-NH-(PEG)9-CH2CH2COOH


Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid
Synonym More Synonyms

 Fmoc-NH-(PEG)9-CH2CH2COOH Biological Activity

Description Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Yang Y,et al. Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4. Bioorg Med Chem. 2016 Nov 1;24(21):5393-5399.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 803.9±65.0 °C at 760 mmHg
Molecular Formula C36H53NO13
Molecular Weight 707.805
Flash Point 440.0±34.3 °C
Exact Mass 707.351685
LogP 0.51
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.526

 Synonyms

2,7,10,13,16,19,22,25,28,31-Decaoxa-4-azatetratriacontan-34-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid
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