S07-2001

Modify Date: 2024-09-17 14:24:42

S07-2001 Structure
S07-2001 structure
Common Name S07-2001
CAS Number 1197904-57-6 Molecular Weight 335.38
Density N/A Boiling Point N/A
Molecular Formula C15H17N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S07-2001


S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer drug resistance[1].

 Names

Name S07-2001

 S07-2001 Biological Activity

Description S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer drug resistance[1].
Related Catalog
Target

S07-2001 (50 μM) reduces 27% of MCF-7 cell viability administrated with Doxorubicin[1].

References

[1]. Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.

 Chemical & Physical Properties

Molecular Formula C15H17N3O4S
Molecular Weight 335.38