S07-2005 (racemic)

Modify Date: 2024-09-14 11:40:37

S07-2005 (racemic) Structure
S07-2005 (racemic) structure
Common Name S07-2005 (racemic)
CAS Number 1826337-40-9 Molecular Weight 373.40
Density N/A Boiling Point N/A
Molecular Formula C20H23NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S07-2005 (racemic)


S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer drug resistance[1].

 Names

Name S07-2005 (racemic)

 S07-2005 (racemic) Biological Activity

Description S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer drug resistance[1].
Related Catalog
Target

IC50: 2.88 ± 1.10 μM (AKR1C1), 0.13 ± 0.03 μM (AKR1C3), 0.75 ± 0.32 μM (AKR1C4)[1]

References

[1]. Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.

 Chemical & Physical Properties

Molecular Formula C20H23NO6
Molecular Weight 373.40