N-(2-Phenoxyacetyl)guanosine

Modify Date: 2024-01-11 10:08:03

N-(2-Phenoxyacetyl)guanosine Structure
N-(2-Phenoxyacetyl)guanosine structure
Common Name N-(2-Phenoxyacetyl)guanosine
CAS Number 119824-66-7 Molecular Weight 417.37
Density 1.76±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C18H19N5O7 Melting Point 159-160 °C
MSDS N/A Flash Point N/A

 Use of N-(2-Phenoxyacetyl)guanosine


N2-Phenoxyacetylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

 Names

Name Gua(pac)
Synonym More Synonyms

 N-(2-Phenoxyacetyl)guanosine Biological Activity

Description N2-Phenoxyacetylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

 Chemical & Physical Properties

Density 1.76±0.1 g/cm3(Predicted)
Melting Point 159-160 °C
Molecular Formula C18H19N5O7
Molecular Weight 417.37
Exact Mass 417.12800
PSA 171.82000
Storage condition 2-8℃

 Synonyms

N2-phenoxyacetylguanosine
2-N-phenoxyacetylguanosine
2-N-(phenoxyacetyl)guanosine
N2-(phenoxyacetyl)guanosine
N-[9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-2-phenoxy-acetamide
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