Coptisine sulfate

Modify Date: 2024-01-02 14:20:59

Coptisine sulfate Structure
Coptisine sulfate structure
Common Name Coptisine sulfate
CAS Number 1198398-71-8 Molecular Weight 417.389
Density N/A Boiling Point N/A
Molecular Formula C19H15NO8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Coptisine sulfate


Coptisine Sulfate is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM[1].

 Names

Name Coptisine sulfate
Synonym More Synonyms

 Coptisine sulfate Biological Activity

Description Coptisine Sulfate is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM[1].
Related Catalog
Target

IC50: 6.3 μM (IDO)[1] Ki: 5.8 μM (IDO)[1]

References

[1]. Yu D, et al. The IDO inhibitor coptisine ameliorates cognitive impairment in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2015;43(1):291-302.

 Chemical & Physical Properties

Molecular Formula C19H15NO8S
Molecular Weight 417.389
Exact Mass 417.051849

 Synonyms

6,7-Dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-5-ium hydrogen sulfate
Coptisine sulfate
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