Verlukast

Modify Date: 2024-01-11 07:00:57

Verlukast Structure
Verlukast structure
Common Name Verlukast
CAS Number 120443-16-5 Molecular Weight 515.087
Density 1.3±0.1 g/cm3 Boiling Point 712.3±60.0 °C at 760 mmHg
Molecular Formula C26H27ClN2O3S2 Melting Point N/A
MSDS N/A Flash Point 384.6±32.9 °C

 Use of Verlukast


Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1].

 Names

Name 3-[(R)-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoic acid
Synonym More Synonyms

 Verlukast Biological Activity

Description Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1].
Related Catalog
Target

leukotriene receptor[1]

References

[1]. Dahlén B, et al. Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. Thorax. 1993;48(12):1205-1210.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 712.3±60.0 °C at 760 mmHg
Molecular Formula C26H27ClN2O3S2
Molecular Weight 515.087
Flash Point 384.6±32.9 °C
Exact Mass 514.115173
PSA 121.10000
LogP 5.93
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.687

 Synonyms

3-{[(R)-{3-[(E)-2-(7-Chloroquinolin-2-yl)vinyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid
Propanoic acid, 3-[[(R)-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-
MK 679
3-(((aR)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-a-((2-(dimethylcarbamoyl)ethyl)thio)benzyl)thio)propionic Acid
3-{[(R)-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid
Verlukastum
(R-(E))-3-(((3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoic Acid
3-(((αR)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-α-((2-(dimethylcarbamoyl)ethyl)thio)benzyl)thio)propionic acid
3-{[(R)-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid
MK-0679
VERLUKAST