6-O-Nicotinoylscutebarbatine G

Modify Date: 2024-02-02 02:19:42

6-O-Nicotinoylscutebarbatine G Structure
6-O-Nicotinoylscutebarbatine G structure
Common Name 6-O-Nicotinoylscutebarbatine G
CAS Number 1206805-30-2 Molecular Weight 576.64
Density 1.3±0.1 g/cm3 Boiling Point 732.3±60.0 °C at 760 mmHg
Molecular Formula C32H36N2O8 Melting Point N/A
MSDS N/A Flash Point 237.9±26.4 °C

 Use of 6-O-Nicotinoylscutebarbatine G


6-O-Nicotinoylscutebarbatine G is an alkaloid that can be isolated from Scutellaria barbata.6-O-Nicotinoylscutebarbatine has cytotoxic activities against HONE-1, KB and HT29 cells with IC50s of 3.1, 2.1 and 5.7 μM, respectively[1].

 Names

Name (3R,4aR,5S,6R,6aR,10R,10aS,10bR)-5-hydroxy-4a,6a,7,10b-tetramethyl-5'-oxo-1,2,4a,4',5,5',6,6a,9,10,10a,10b-dodecahydro-2'H-spiro[benzo[f]chromene-3,3'-furan]-6,10-diyl dinicotinate
Synonym More Synonyms

 6-O-Nicotinoylscutebarbatine G Biological Activity

Description 6-O-Nicotinoylscutebarbatine G is an alkaloid that can be isolated from Scutellaria barbata.6-O-Nicotinoylscutebarbatine has cytotoxic activities against HONE-1, KB and HT29 cells with IC50s of 3.1, 2.1 and 5.7 μM, respectively[1].
Related Catalog
References

[1]. Dai SJ, et al. Two new neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities. J Asian Nat Prod Res. 2009;11(5):451-6.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 732.3±60.0 °C at 760 mmHg
Molecular Formula C32H36N2O8
Molecular Weight 576.64
Flash Point 237.9±26.4 °C
Exact Mass 546.225342
PSA 134.14000
LogP 3.55
Vapour Pressure 0.0±5.4 mmHg at 25°C
Index of Refraction 1.611

 Safety Information

Hazard Codes Xi

 Synonyms

1,3,4-Cyclopentatriene-1-carboxylic acid, (3R,4a'R,5'S,6'R,6a'R,10'R,10a'S,10b'R)-1',2',4,4'a,5,5',6',6'a,9',10',10'a,10'b-dodecahydro-5'-hydroxy-4'a,6'a,7',10'b-tetramethyl-5-oxospiro[furan-3(2H),3'-[3H]naphtho[2,1-b]pyran]-6',10'-diyl ester
(3R,4aR,5S,6R,6aR,10R,10aS,10bR)-5-Hydroxy-4a,6a,7,10b-tetramethyl-5'-oxo-1,2,4',4a,5,5',6,6a,9,10,10a,10b-dodecahydrospiro[benzo[f]chromene-3,3'-furan]-6,10-diyl bis(1,3,4-cyclopentatriene-1-carboxylate)
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