1206805-30-2

1206805-30-2 structure

Name: 6-O-Nicotinoylscutebarbatine G
Chemical Name: (3R,4aR,5S,6R,6aR,10R,10aS,10bR)-5-hydroxy-4a,6a,7,10b-tetramethyl-5'-oxo-1,2,4a,4',5,5',6,6a,9,10,10a,10b-dodecahydro-2'H-spiro[benzo[f]chromene-3,3'-furan]-6,10-diyl dinicotinate
CAS Number: 1206805-30-2
Molecular Formula: C₃₂H₃₆N₂O₈
Molecular Weight: 576.64
Catalog: Natural product Moss
Create Date: 2017-11-16 08:49:13
Modify Date: 2024-02-02 02:19:42
6-O-Nicotinoylscutebarbatine G is an alkaloid that can be isolated from Scutellaria barbata.6-O-Nicotinoylscutebarbatine has cytotoxic activities against HONE-1, KB and HT29 cells with IC50s of 3.1, 2.1 and 5.7 μM, respectively[1].

Name	(3R,4aR,5S,6R,6aR,10R,10aS,10bR)-5-hydroxy-4a,6a,7,10b-tetramethyl-5'-oxo-1,2,4a,4',5,5',6,6a,9,10,10a,10b-dodecahydro-2'H-spiro[benzo[f]chromene-3,3'-furan]-6,10-diyl dinicotinate
Synonyms	1,3,4-Cyclopentatriene-1-carboxylic acid, (3R,4a'R,5'S,6'R,6a'R,10'R,10a'S,10b'R)-1',2',4,4'a,5,5',6',6'a,9',10',10'a,10'b-dodecahydro-5'-hydroxy-4'a,6'a,7',10'b-tetramethyl-5-oxospiro[furan-3(2H),3'-[3H]naphtho[2,1-b]pyran]-6',10'-diyl ester (3R,4aR,5S,6R,6aR,10R,10aS,10bR)-5-Hydroxy-4a,6a,7,10b-tetramethyl-5'-oxo-1,2,4',4a,5,5',6,6a,9,10,10a,10b-dodecahydrospiro[benzo[f]chromene-3,3'-furan]-6,10-diyl bis(1,3,4-cyclopentatriene-1-carboxylate)

Description	6-O-Nicotinoylscutebarbatine G is an alkaloid that can be isolated from Scutellaria barbata.6-O-Nicotinoylscutebarbatine has cytotoxic activities against HONE-1, KB and HT29 cells with IC50s of 3.1, 2.1 and 5.7 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Dai SJ, et al. Two new neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities. J Asian Nat Prod Res. 2009;11(5):451-6.

Hazard Codes	Xi