Venlafaxine-d10 hydrochloride

Modify Date: 2024-01-05 13:30:54

Venlafaxine-d10 hydrochloride Structure
Venlafaxine-d10 hydrochloride structure
Common Name Venlafaxine-d10 hydrochloride
CAS Number 1216539-56-8 Molecular Weight 323.92433778
Density N/A Boiling Point N/A
Molecular Formula C17H18ClD10NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Venlafaxine-d10 hydrochloride


Venlafaxine-d10 (Wy 45030-d10) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine (Wy 45030) hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1][2].

 Names

Name D,L-Venlafaxine-d10 Hydrochloride

 Venlafaxine-d10 hydrochloride Biological Activity

Description Venlafaxine-d10 (Wy 45030-d10) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine (Wy 45030) hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

[3]. Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121(1-2):70-5.

 Chemical & Physical Properties

Molecular Formula C17H18ClD10NO2
Molecular Weight 323.92433778
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