Tiamulin-d10 hydrochloride

Modify Date: 2024-01-15 12:44:56

Tiamulin-d10 hydrochloride Structure
Tiamulin-d10 hydrochloride structure
Common Name Tiamulin-d10 hydrochloride
CAS Number 1322626-74-3 Molecular Weight 540.26
Density N/A Boiling Point N/A
Molecular Formula C28H38D10ClNO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tiamulin-d10 hydrochloride


Tiamulin-d10 (Thiamutilin-d10) hydrochloride is the deuterium labeled Tiamulin. Tiamulin (Thiamutilin) is a diterpenic compound that widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia[1][2][3].

 Names

Name Tiamulin-d10 hydrochloride

 Tiamulin-d10 hydrochloride Biological Activity

Description Tiamulin-d10 (Thiamutilin-d10) hydrochloride is the deuterium labeled Tiamulin. Tiamulin (Thiamutilin) is a diterpenic compound that widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia[1][2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Noa M, et al. Tiamulin-nitrovin interaction in pigs: a case report and experimental reproduction. Vet Hum Toxicol. 2000 Oct;42(5):286-8.

[3]. Dreyfuss J, et al. Metabolism of tritium- and carbon-14-labeled tiamulin in dogs, rats, and pigs. J Antibiot (Tokyo). 1979 May;32(5):496-503.

[4]. Islam KM, et al. The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review. Poult Sci. 2009 Nov;88(11):2353-9.

 Chemical & Physical Properties

Molecular Formula C28H38D10ClNO4S
Molecular Weight 540.26