DO3A tert-Butyl ester

Modify Date: 2024-01-11 00:00:03

DO3A tert-Butyl ester Structure
DO3A tert-Butyl ester structure
Common Name DO3A tert-Butyl ester
CAS Number 122555-91-3 Molecular Weight 514.698
Density 1.0±0.1 g/cm3 Boiling Point 561.6±50.0 °C at 760 mmHg
Molecular Formula C26H50N4O6 Melting Point N/A
MSDS N/A Flash Point 293.4±30.1 °C

 Use of DO3A tert-Butyl ester


DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride.

 Names

Name tert-butyl 2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetate
Synonym More Synonyms

 DO3A tert-Butyl ester Biological Activity

Description DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride.
Related Catalog
References

[1]. Martha L Gilbert, et al. A new synthetic route to 2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecane. doi:10.1016/S0040-4039(00)73873-1

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 561.6±50.0 °C at 760 mmHg
Molecular Formula C26H50N4O6
Molecular Weight 514.698
Flash Point 293.4±30.1 °C
Exact Mass 514.373047
PSA 100.65000
LogP 4.21
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.467

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26

 Synthetic Route

~84%

DO3A tert-Butyl ester Structure

DO3A tert-Butyl...

CAS#:122555-91-3

Literature: Tetrahedron Letters, , vol. 54, # 8 p. 918 - 920

~35%

DO3A tert-Butyl ester Structure

DO3A tert-Butyl...

CAS#:122555-91-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 24 p. 7410 - 7413

~%

DO3A tert-Butyl ester Structure

DO3A tert-Butyl...

CAS#:122555-91-3

Detail
Literature: WO2005/32599 A1, ; Page/Page column 22-24; figure 12 ;

~76%

DO3A tert-Butyl ester Structure

DO3A tert-Butyl...

CAS#:122555-91-3

Literature: WO2005/3105 A1, ; Page/Page column 6 ;

~%

DO3A tert-Butyl ester Structure

DO3A tert-Butyl...

CAS#:122555-91-3

Literature: Amino Acids, , vol. 46, # 2 p. 449 - 457

 Synonyms

DO3A-t-Bu-ester
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, tris(1,1-dimethylethyl) ester
1,4,7-Tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane
DO3A-tris-tbutyl ester
1,4,7,10-tetraazacyclododecane-1,4,7-tris(t-butyl acetate)
TRI-T-BUTYL 1 4 7 10-TETRAAZACYCLODODECA
DO3AtBu
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester
Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7-triacetate
N',N",N'"-tris(t-Bu)DO3A
2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid tri-tert-butyl ester
MFCD05865261
1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid tris(1,1-dimethylethyl) ester
DO3A-tris-tert-butyl ester
Tris(2-methyl-2-propanyl) 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
Tri-tert-butyl 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
tert-butyl (1,4,7,10-tetraaza-4,7-bis(((tert-butyl)oxycarbonyl)methyl)cyclododecyl)acetate
DO3A tert-Butyl ester
Top Suppliers:I want be here



Get all suppliers and price by the below link:

DO3A tert-Butyl ester suppliers


Price: $158/10mM*1mLinDMSO

Reference only. check more DO3A tert-Butyl ester price

Related Compounds: More...
threonine tert-butyl ester
66748-90-1
Moexipril tert-Butyl Ester Maleic Acid Salt
103733-40-0
Norleucine tert-butyl ester hydrochloride
119483-48-6
Ethanol,1,1'-thiobis[2,2,2-trichloro-
18271-97-1
L-Alanylglycine tert-butyl ester
66880-74-8
(R)-Phenylglycine tert-butyl ester hydrochloride
256478-95-2
Atorvastatin Acetonide tert-Butyl Ester
125971-95-1
L-Alanine tert-butyl ester
21691-50-9
phenylalanyl-valine tert-butyl ester
14611-28-0
(3R)-3-{[(2RS,3SR)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}heptanoic acid
2227690-84-6
(4R)-3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpropanoyl]-1,3-thiazolidine-4-carboxylic acid
2171203-97-5
2-{4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]-1H-pyrazol-1-yl}acetic acid
2172278-80-5
3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-difluoropropanamido]propanoic acid
2171978-91-7
(2R)-2-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}propanoic acid
2171264-97-2
3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanamido]-2-hydroxypropanoic acid
2171368-78-6
3-[6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]-2-hydroxypropanoic acid
2172466-85-0
3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]-2-hydroxypropanoic acid
2171441-97-5
(2R)-2-[2-ethyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]butanoic acid
2171183-00-7
(3R)-1-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopropanecarbonyl]piperidine-3-carboxylic acid
2171286-07-8