[D-Ala2] -Deltorphin II

Modify Date: 2024-01-11 18:26:58

[D-Ala2] -Deltorphin II Structure
[D-Ala2] -Deltorphin II structure
Common Name [D-Ala2] -Deltorphin II
CAS Number 122752-16-3 Molecular Weight 782.88300
Density 1.272 g/cm3 Boiling Point 1256.2ºC at 760 mmHg
Molecular Formula C38H54N8O10 Melting Point N/A
MSDS Chinese USA Flash Point 713.5ºC

 Use of [D-Ala2] -Deltorphin II


Deltorphin 2 is a selective peptide agonit for the δ opioid receptor.

 Names

Name [D-Ala2]-Deltorphin II
Synonym More Synonyms

 [D-Ala2] -Deltorphin II Biological Activity

Description Deltorphin 2 is a selective peptide agonit for the δ opioid receptor.
Related Catalog
Target

δ opioid receptor[1]

In Vitro Deltorphin 2 ([D-Ala2]-Deltorphin II) is enzymatically stable, amphibian heptapeptides that has a high affinity and selectivity for delta-opioid receptor. Deltorphin 2 is the most selective natural delta opioid receptor agonist[1].
References

[1]. Thomas SA, et al. Structure-activity relationships of a series of [D-Ala2]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. J Pharmacol Exp Ther. 1997 May;281(2):817-25.

 Chemical & Physical Properties

Density 1.272 g/cm3
Boiling Point 1256.2ºC at 760 mmHg
Molecular Formula C38H54N8O10
Molecular Weight 782.88300
Flash Point 713.5ºC
Exact Mass 782.39600
PSA 301.24000
LogP 2.47290
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.575
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles25

More Articles
Membrane partitioning of various delta-opioid receptor forms before and after agonist activations: the effect of cholesterol.

Biochim. Biophys. Acta 1778(6) , 1483-92, (2008)

Lipid rafts depicted as densely packed and thicker membrane microdomains, based on the dynamic clustering of cholesterol and sphingolipids, may help as platforms involved in a wide variety of cellular...

Delta opioid receptor-mediated analgesia is not altered in preprotachykinin A knockout mice.

Eur. J. Neurosci. 32(11) , 1921-9, (2010)

We have shown that delta opioid receptor (DOPR)-mediated analgesia was enhanced in the complete Freund's adjuvant (CFA) model of inflammation. This effect is thought to originate from translocation of...

Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE.

Pharm. Res. 26(5) , 1226-35, (2009)

To investigate whether conjunctival epithelial cells express transport processes for opioid peptides.We monitored the uptake of [(3)H]deltorphin II and [(3)H]DADLE, two hydrolysis-resistant synthetic ...

 Synonyms

Tyr-D-Ala-Phe-Glu-Val-Val-Gly amide
M.W. 782.89 C38H54N8O10
DELTORPHIN B
DADELT II
H-Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2
H2N-Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2
deltorphin II
TYR-D-ALA-PHE-GLU-VAL-VAL-GLY-NH2
DELTORPHIN II
Deltorphin 2
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