3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile

Modify Date: 2024-02-05 18:05:08

3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile Structure
3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile structure
 Common Name 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile
CAS Number 123548-56-1 Molecular Weight 367.74100
Density 1.43g/cm3 Boiling Point 588.3ºC at 760mmHg
Molecular Formula C15H14ClN3O6 Melting Point N/A
MSDS N/A Flash Point 309.6ºC

 Use of 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile


Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].

 Names

Name [2-[3-[(2-acetyloxyacetyl)amino]-2-chloro-5-cyanoanilino]-2-oxoethyl] acetate
Synonym More Synonyms

  Biological Activity

Description Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].
Related Catalog
References

[1]. Watanabe A, et al. Effect of TYB-2285 on antigen-induced histamine release from mouse bone marrow-derived persisting cells (P-cells) primed with interleukin-3-containing conditioned medium (IL3-CM). Gen Pharmacol. 1993 Sep;24(5):1207-11.  

 Chemical & Physical Properties

Density 1.43g/cm3
Boiling Point 588.3ºC at 760mmHg
Molecular Formula C15H14ClN3O6
Molecular Weight 367.74100
Flash Point 309.6ºC
Exact Mass 367.05700
PSA 141.57000
LogP 2.51388
Vapour Pressure 8.03E-14mmHg at 25°C
Index of Refraction 1.571

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

Acreozast
Acreozst
Tyb-2285
UNII-84DZ9RW4WK
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Chemsrc provides CAS#:123548-56-1 MSDS, density, melting point, boiling point, structure, etc. Its name is 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile>> amp version: 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile

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