123548-56-1

123548-56-1 structure
123548-56-1 structure
  • Name: 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile
  • Chemical Name: [2-[3-[(2-acetyloxyacetyl)amino]-2-chloro-5-cyanoanilino]-2-oxoethyl] acetate
  • CAS Number: 123548-56-1
  • Molecular Formula: C15H14ClN3O6
  • Molecular Weight: 367.74100
  • Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
  • Create Date: 2016-01-31 16:06:27
  • Modify Date: 2024-02-05 18:05:08
  • Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].

Name [2-[3-[(2-acetyloxyacetyl)amino]-2-chloro-5-cyanoanilino]-2-oxoethyl] acetate
Synonyms Acreozast
Acreozst
Tyb-2285
UNII-84DZ9RW4WK
Description Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].
Related Catalog
References

[1]. Watanabe A, et al. Effect of TYB-2285 on antigen-induced histamine release from mouse bone marrow-derived persisting cells (P-cells) primed with interleukin-3-containing conditioned medium (IL3-CM). Gen Pharmacol. 1993 Sep;24(5):1207-11.  

Density 1.43g/cm3
Boiling Point 588.3ºC at 760mmHg
Molecular Formula C15H14ClN3O6
Molecular Weight 367.74100
Flash Point 309.6ºC
Exact Mass 367.05700
PSA 141.57000
LogP 2.51388
Vapour Pressure 8.03E-14mmHg at 25°C
Index of Refraction 1.571
Precursor  2

DownStream  0