SPDP-dPEG

Modify Date: 2024-01-06 11:35:02

SPDP-dPEG Structure
SPDP-dPEG structure
Common Name SPDP-dPEG
CAS Number 1252257-56-9 Molecular Weight 735.863
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C31H49N3O13S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SPDP-dPEG


LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

 Names

Name N-{27-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl}-3-(2-pyridinyldisulfanyl)propanamide
Synonym More Synonyms

 SPDP-dPEG Biological Activity

Description LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

References

[1]. Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C31H49N3O13S2
Molecular Weight 735.863
Exact Mass 735.270691
LogP -2.32
Index of Refraction 1.555

 Synonyms

Propanamide, N-[27-[(2,5-dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl]-3-(2-pyridinyldithio)-
N-{27-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-27-oxo-3,6,9,12,15,18,21,24-octaoxaheptacos-1-yl}-3-(2-pyridinyldisulfanyl)propanamide
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