AbK

Modify Date: 2024-01-10 11:58:05

AbK Structure
AbK structure
Common Name AbK
CAS Number 1253643-88-7 Molecular Weight 272.30
Density N/A Boiling Point N/A
Molecular Formula C11H20N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AbK


H-L-Photo-lysine is a diazirine-containing lysine amino acid and is a photo-cross-linker. H-L-Photo-lysine can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. H-L-Photo-lysine acts as a UV light-activated photo-crosslinking probe[1][2][3].

 Names

Name H-L-Photo-lysine

 AbK Biological Activity

Description H-L-Photo-lysine is a diazirine-containing lysine amino acid and is a photo-cross-linker. H-L-Photo-lysine can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. H-L-Photo-lysine acts as a UV light-activated photo-crosslinking probe[1][2][3].
Related Catalog
In Vitro Photo-lysine, which is readily incorporated into proteins by native mammalian translation machinery, can be used to capture and identify proteins that recognize lysine post-translational modifications (PTMs), including 'readers' and 'erasers' of histone modifications[2].
References

[1]. Ai HW, et al. Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem. 2011 Aug 16;12(12):1854-7.

[2]. Chatterjee A, et al. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11803-8.

[3]. Yang T, et al. Photo-lysine captures proteins that bind lysine post-translational modifications. Nat Chem Biol. 2016 Feb;12(2):70-2.

 Chemical & Physical Properties

Molecular Formula C11H20N4O4
Molecular Weight 272.30