Levofloxacin-13C,d3

Modify Date: 2024-01-14 20:32:14

Levofloxacin-13C,d3 structure	Common Name	Levofloxacin-13C,d3
	CAS Number	1261398-33-7	Molecular Weight	365.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇₁₃CH₁₇D₃FN₃O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07, GHS08	Signal Word	Danger

Use of Levofloxacin-13C,d3

Levofloxacin-13C,d3 is the 13C- and deuterium labeled.

Name	Levofloxacin-13C,d3

Description	Levofloxacin-13C,d3 is the 13C- and deuterium labeled.
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[83].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [2]. Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86. [3]. Pradeep, A.R., et al., Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. J Investig Clin Dent, 2014. [4]. Lee, B.T., et al., Efficacy of Levofloxacin in the Treatment of BK Viremia: A Multicenter, Double-Blinded, Randomized, Placebo-Controlled Trial. Clin J Am Soc Nephrol, 2014.

Molecular Formula	C₁₇₁₃CH₁₇D₃FN₃O₄
Molecular Weight	365.38

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H302-H317-H334-H361d-H362
Precautionary Statements	P261-P263-P280-P342 + P311