Biotin-PEG3-OH

Modify Date: 2024-01-23 12:52:33

Biotin-PEG3-OH Structure
Biotin-PEG3-OH structure
Common Name Biotin-PEG3-OH
CAS Number 1263044-40-1 Molecular Weight 375.48
Density N/A Boiling Point N/A
Molecular Formula C16H29N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG3-OH


Biotin-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG3-alcohol

 Biotin-PEG3-OH Biological Activity

Description Biotin-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H29N3O5S
Molecular Weight 375.48