Biotin-PEG3-propionic hydrazide

Modify Date: 2024-01-04 10:23:40

Biotin-PEG3-propionic hydrazide Structure
Biotin-PEG3-propionic hydrazide structure
Common Name Biotin-PEG3-propionic hydrazide
CAS Number 1381861-94-4 Molecular Weight 461.576
Density 1.2±0.1 g/cm3 Boiling Point 813.7±65.0 °C at 760 mmHg
Molecular Formula C19H35N5O6S Melting Point N/A
MSDS N/A Flash Point 445.9±34.3 °C

 Use of Biotin-PEG3-propionic hydrazide


Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

 Names

Name N-(2-{2-[2-(3-Hydrazino-3-oxopropoxy)ethoxy]ethoxy}ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
Synonym More Synonyms

 Biotin-PEG3-propionic hydrazide Biological Activity

Description Biotin-PEG3-propionic hydrazide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 813.7±65.0 °C at 760 mmHg
Molecular Formula C19H35N5O6S
Molecular Weight 461.576
Flash Point 445.9±34.3 °C
Exact Mass 461.230804
LogP -2.76
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.526
Storage condition 2-8°C

 Synonyms

N-(2-{2-[2-(3-Hydrazino-3-oxopropoxy)ethoxy]ethoxy}ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
4,7,10-Trioxa-13-azaoctadecan-1-oic acid, 18-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-14-oxo-, hydrazide
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