SGK1-IN-1 structure
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Common Name | SGK1-IN-1 | ||
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CAS Number | 1279829-87-6 | Molecular Weight | 418.83 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C17H12ClFN6O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of SGK1-IN-1SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM. |
Name | SGK1-IN-1 |
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Description | SGK1-IN-1 is a highly active and selective inhibitor of SGK-1, with an IC50 of 1 nM. |
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Related Catalog | |
Target |
IC50: 1 nM (SGK-1)[1][2]. |
In Vitro | SGK1-IN-1 (14n) shows an acceptable SGK isoform selectivity with a good activity on hSGK2 and a moderate activity on the hSGK3, with IC50s of 1, 41 nM at 10 μM and 50 μM ATP concentration, respectively. SGK1-IN-1 also displays cellular activity in a SGK1-dependent phosphorylation of GSK3β assay in U2OS cells with activities of 0.69 μM[2]. |
References |
Molecular Formula | C17H12ClFN6O2S |
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Molecular Weight | 418.83 |