Sphingosine (d12:1)

Modify Date: 2024-01-10 09:33:45

Sphingosine (d12:1) Structure
Sphingosine (d12:1) structure
Common Name Sphingosine (d12:1)
CAS Number 128427-86-1 Molecular Weight 215.33200
Density N/A Boiling Point N/A
Molecular Formula C12H25NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sphingosine (d12:1)


C12-Sphingosine is a short-chain Sphingosine homologue. C12-Sphingosine inhibits serine palmitoyltransferase activity in primary cultured cerebellar cells[1].

 Names

Name (2S,3R,4E)-2-amino-4-dodecene-1,3-diol
Synonym More Synonyms

 Sphingosine (d12:1) Biological Activity

Description C12-Sphingosine is a short-chain Sphingosine homologue. C12-Sphingosine inhibits serine palmitoyltransferase activity in primary cultured cerebellar cells[1].
Related Catalog
In Vitro C12-Sphingosine inhibits dr novo sphingosine and sphingolipid biosynthesis in murine cerebellar cells. C12-Sphingosine decreases serine palrnitoyltransferase activity in primary cultured neurons in a time- and concentration-dependent manner[1].
References

[1]. E C Mandon, et al. Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases. Eur J Biochem. 1991 Jun 15;198(3):667-74.

 Chemical & Physical Properties

Molecular Formula C12H25NO2
Molecular Weight 215.33200
Exact Mass 215.18900
PSA 66.48000
LogP 2.28390

 Synonyms

D-erythro-sphingosine
C12-Sphingosine
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