3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine

Modify Date: 2024-01-19 17:11:03

3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine Structure
3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine structure
Common Name 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine
CAS Number 128496-10-6 Molecular Weight 454.40
Density N/A Boiling Point N/A
Molecular Formula C23H19FN2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine


3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)uracil
Synonym More Synonyms

  Biological Activity

Description 3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C23H19FN2O7
Molecular Weight 454.40
Exact Mass 454.11800
PSA 116.69000
LogP 1.85470

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

1-(2-deoxy-2-fluoro-3,5-di-O-benzoyl-