5-Aminolevulinic acid-4-13C hydrochloride

Modify Date: 2024-01-11 07:25:45

5-Aminolevulinic acid-4-13C hydrochloride structure	Common Name	5-Aminolevulinic acid-4-13C hydrochloride
	CAS Number	129720-94-1	Molecular Weight	168.58
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₁₃CH₁₀ClNO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5-Aminolevulinic acid-4-13C hydrochloride

5-Aminolevulinic acid-4-13C (hydrochloride) is the 13C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].

Name	5-Aminolevulinic acid-4-13C hydrochloride

Description	5-Aminolevulinic acid-4-13C (hydrochloride) is the 13C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].
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In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401. [3]. Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.

Molecular Formula	C₄₁₃CH₁₀ClNO₃
Molecular Weight	168.58

5-Aminolevulinic acid-4-13C hydrochloride

Use of 5-Aminolevulinic acid-4-13C hydrochloride

Names

Biological Activity

Chemical & Physical Properties