Argipressin Acetate
Modify Date: 2024-01-02 18:52:58
Argipressin Acetate structure
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Common Name | Argipressin Acetate | ||
|---|---|---|---|---|
| CAS Number | 129979-57-3 | Molecular Weight | 1144.28000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C48H69N15O14S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Argipressin AcetateArgipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4]. |
| Name | <8-arginine>vasopressin |
|---|---|
| Synonym | More Synonyms |
| Description | Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4]. |
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| Related Catalog | |
| In Vitro | Argipressin (Arg8-vasopressin) (acetate) 在啮齿动物和人类 β 细胞中诱导增殖并阻止细胞因子诱导的细胞凋亡[1]。 Cell Proliferation Assay[1] Cell Line: clonal BRIN BD11 and 1.1B4 cells Concentration: 10-6 M Incubation Time: 2 h Result: Increased proliferation of rodent and human beta-cells. Apoptosis Analysis[1] Cell Line: clonal BRIN BD11 and 1.1B4 cells Concentration: 10-6 M Incubation Time: 2 h Result: Protected against cytokine-induced beta-cell apoptosis. |
| In Vivo | Argipressin (diacetate) (AVP (diacetate)) (25 nmol/kg bw; 腹腔内注射; 一次) 显着降低小鼠的总体 AUC 葡萄糖值，但不增加小鼠的胰岛素水平[1]。 Animal Model: NIH Swiss mice (adult; male; 12-14weeks)[1] Dosage: 25 nmol/kg bw Administration: AVP (25 nmol/kg bw; intraperitoneal injection; once) Result: Reduced (P<0.001) overall AUC glucose values，but not increased insulin levels in mice. |
| References |
| Molecular Formula | C48H69N15O14S2 |
|---|---|
| Molecular Weight | 1144.28000 |
| Exact Mass | 1143.46000 |
| PSA | 549.33000 |
| LogP | 1.25190 |
| Storage condition | 2-8°C |
| [ARG8]VASOPRESSIN TFA |
| ARGIPRESSIN ACETATE |
| [Arg8]Vasopressin acetate |
| ArgipressinAcetate |
| Argipressin Acetate |