Cetrorelix diacetate
Modify Date: 2024-01-11 16:27:30
Cetrorelix diacetate structure
|
Common Name | Cetrorelix diacetate | ||
|---|---|---|---|---|
| CAS Number | 130143-01-0 | Molecular Weight | 1431.038 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1768.4ºC at 760 mmHg | |
| Molecular Formula | C70H92ClN17O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 1023.3ºC | |
Use of Cetrorelix diacetateCetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM[1]. |
| Name | Cetrorelix acetate |
|---|---|
| Synonym | More Synonyms |
| Description | Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.21 nM GnRH[1]. |
| In Vitro | Cetrorelix diacetate inhibits growth of ES-2 cell line at 1000 ng/ml. Cetrorelix diacetate has comparable antiproliferative effects as GnRH-I agonists indicating that the dichotomy of GnRH-I agonists and antagonists might not apply to the GnRH-I system in cancer cells[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 1768.4ºC at 760 mmHg |
| Molecular Formula | C70H92ClN17O14 |
| Molecular Weight | 1431.038 |
| Flash Point | 1023.3ºC |
| Exact Mass | 1429.669800 |
| PSA | 518.21000 |
| LogP | 2.69 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.668 |
| N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N-carbamoyl-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide |
| N-Carbamoyl-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-N-[(2S)-3-(4-acetoxyphenyl)-2-{[3-(3-pyridinyl)-D-alanyl-O-acetyl-L-seryl]amino}propanoyl]-N-[N-acetyl-3-(2-naphthyl)-D-alanyl]-N-[(2R)-2-amino ; -3-(4-chlorophenyl)propanoyl]-D-alaninamide |
| Cetrorenlin Acetate |
| D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl- |
| (2S)-N-[(2R)-1-Amino-1-oxopropan-2-yl]-1-[(2S,5S,8R,11S,14S,17R,20R,23R)-2-(3-carbamimidamidopropyl)-8-[3-(carbamoylamino)propyl]-20-(4-chlorobenzyl)-11-(4-hydroxybenzyl)-14-(hydroxymethyl)-5-isobutyl-23-(2-naphthylmethyl)-4,7,10,13,16,19,22,25-octaoxo-17-(pyridin-3-ylmethyl)-3,6,9,12,15,18,21,24-octaazahexacosan-1-oyl]pyrrolidine-2-carboxamide (non-preferred name) |
| N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide |
| N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(pyridin-3-yl)-D-alanyl-L-seryl-L-tyrosyl-N-carbamoyl-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide |
| Cetrorelix |
| D-Alaninamide, N-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-N-[N-acetyl-3-(2-naphthalenyl)-D-alanyl]-N-[(2S)-2-[[(2S)-3-(acetyloxy)-2-[[(2R)-2-amino-1-oxo-3-(3-pyridinyl)propyl]amino ]-1-oxopropyl]amino]-3-[4-(acetyloxy)phenyl]-1-oxopropyl]-N-[(2R)-2-amino-3-(4-chlorophenyl)-1-oxopropyl]- |
| cetrorelixum [INN_la] |