Demethoxypiplartine

Modify Date: 2024-01-11 19:09:45

Demethoxypiplartine Structure
Demethoxypiplartine structure
Common Name Demethoxypiplartine
CAS Number 130263-10-4 Molecular Weight 287.31
Density 1.2±0.1 g/cm3 Boiling Point 449.6±45.0 °C at 760 mmHg
Molecular Formula C16H17NO4 Melting Point 116-117℃ (methanol )
MSDS N/A Flash Point 225.7±28.7 °C

 Use of Demethoxypiplartine


Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL[1].

 Names

Name 1-[3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-2-one
Synonym More Synonyms

 Demethoxypiplartine Biological Activity

Description Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL[1].
Related Catalog
References

[1]. Shi YN, et al. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum. Planta Med. 2017 Jan;83(1-02):143-150.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 449.6±45.0 °C at 760 mmHg
Melting Point 116-117℃ (methanol )
Molecular Formula C16H17NO4
Molecular Weight 287.31
Flash Point 225.7±28.7 °C
Exact Mass 287.115753
PSA 55.84000
LogP 2.58
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.593

 Safety Information

Hazard Codes Xi

 Synonyms

2(1H)-Pyridinone, 1-[(2E)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]-5,6-dihydro-
Demethoxypiplartine
1-[(2E)-3-(3,4-Dimethoxyphenyl)-2-propenoyl]-5,6-dihydro-2(1H)-pyridinone
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