3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine

Modify Date: 2024-01-09 11:49:26

3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine Structure
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine structure
Common Name 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine
CAS Number 131474-72-1 Molecular Weight 659.88
Density 1.32±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C30H45N5O8Si2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine


N2-Phenoxyacetyl-3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

 Names

Name N-[9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-6-oxo-3H-purin-2-yl]-2-phenoxyacetamide
Synonym More Synonyms

  Biological Activity

Description N2-Phenoxyacetyl-3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

 Chemical & Physical Properties

Density 1.32±0.1 g/cm3(Predicted)
Molecular Formula C30H45N5O8Si2
Molecular Weight 659.88
Exact Mass 659.28100
PSA 162.80000
LogP 5.41360
Storage condition 2-8℃

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Guanosine,N-(phenoxyacetyl)-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]