Imigliptin dihydrochloride
Modify Date: 2024-01-18 14:32:27
Imigliptin dihydrochloride structure
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Common Name | Imigliptin dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1314944-07-4 | Molecular Weight | 376.455 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 595.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C21H26Cl2N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 313.8±30.1 °C | |
Use of Imigliptin dihydrochlorideA novel potent, selective, orally available DPP-4 inhibitor with IC50 of 9 nM; displays no activity against DPP-8 and DPP-9 (IC50>100 uM); shows strong effects on db/db mice in lowing glucose level, reducing AUC of oral glucose tolerance, decreasing TG and HbA1c levels, and protecting beta-cell. Diabetes Phase 2 Clinical |
| Name | Imigliptin |
|---|---|
| Synonym | More Synonyms |
| Description | A novel potent, selective, orally available DPP-4 inhibitor with IC50 of 9 nM; displays no activity against DPP-8 and DPP-9 (IC50>100 uM); shows strong effects on db/db mice in lowing glucose level, reducing AUC of oral glucose tolerance, decreasing TG and HbA1c levels, and protecting beta-cell. Diabetes Phase 2 Clinical |
|---|---|
| References | References 1. Shu C, et al. ACS Med Chem Lett. 2014 Jun 16;5(8):921-6. 2. Liu D, et al. Eur J Pharm Sci. 2016 Jun 30;89:73-82. View Related Products by Target Dipeptidyl Peptidase (DPP) Diabetes |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 595.3±50.0 °C at 760 mmHg |
| Molecular Formula | C21H26Cl2N6O |
| Molecular Weight | 376.455 |
| Flash Point | 313.8±30.1 °C |
| Exact Mass | 376.201172 |
| LogP | 1.33 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.685 |
| 2-({7-[(3R)-3-Amino-1-piperidinyl]-3,5-dimethyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl}methyl)benzonitrile |
| Benzonitrile, 2-[[7-[(3R)-3-amino-1-piperidinyl]-2,3-dihydro-3,5-dimethyl-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl]methyl]- |
| Imigliptin |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Imigliptin Dihydrochloride
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Imigliptin dihydrochloride
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: Imigliptin dihydrochloride
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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