YSK 05

Modify Date: 2024-01-11 19:30:23

YSK 05 Structure
YSK 05 structure
Common Name YSK 05
CAS Number 1318793-78-0 Molecular Weight 628.07
Density N/A Boiling Point N/A
Molecular Formula C42H77NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of YSK 05


YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo[1].

 Names

Name YSK 05

 YSK 05 Biological Activity

Description YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo[1].
Related Catalog
In Vitro YSK 05 facilitates the endosomal escape of the MEND and thereby enhances the efficacy of siRNA delivery into cytosol and gene silencing[1].
References

[1]. Sato Y, et al. A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo. J Control Release. 2012 Nov 10;163(3):267-76.

 Chemical & Physical Properties

Molecular Formula C42H77NO2
Molecular Weight 628.07
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