KFM19

Modify Date: 2024-01-02 14:15:51

KFM19 Structure
KFM19 structure
Common Name KFM19
CAS Number 133058-72-7 Molecular Weight 318.37100
Density 1.268g/cm3 Boiling Point 584.7ºC at 760mmHg
Molecular Formula C16H22N4O3 Melting Point N/A
MSDS N/A Flash Point 307.4ºC

 Use of KFM19


KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.

 Names

Name 8-(3-oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione
Synonym More Synonyms

 KFM19 Biological Activity

Description KFM19 is a potent, selective Adenosine receptor (A1-receptor) antagonist, with an IC50 of 50 nM.
Related Catalog
Target

IC50: 50 nM (Adenosine receptor)[1]

References

[1]. W.D. Bechtel, et al. KFM 19 antagonizes the adenosine-induced inhibition of electrically evoked acetylcholine release. Eur Neuropsychopharmacol. Sep. 1993, 3(3), Page 433

 Chemical & Physical Properties

Density 1.268g/cm3
Boiling Point 584.7ºC at 760mmHg
Molecular Formula C16H22N4O3
Molecular Weight 318.37100
Flash Point 307.4ºC
Exact Mass 318.16900
PSA 89.75000
LogP 1.54290
Vapour Pressure 1.18E-13mmHg at 25°C
Index of Refraction 1.575
Storage condition 2-8℃

 Synonyms

(+,-)-8-(3-oxocyclopentyl)-1,3-dipropylxanthine
8-(3-oxocyclopentyl)-1,3-di-n-propyl-7H-purine-2,6-dione
Biip 20
1,3-dipropyl-8-(3-oxocyclopentyl)-xanthine
((S)-(-)-8-(3-Oxocyclopentyl)-1,3-dipropyl-7H-purine-2,6-dione)
Kfm 19
8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
KFM19